Key result
CRT in HFrEF linked to normalized monocyte composition reaching non-HFrEF control levels.
Why the study?
The study was conducted to evaluate monocyte subsets in HFrEF patients and assess the effect of cardiac resynchronization therapy on changes in the monocyte compartment.
Does cardiac resynchronization therapy normalize altered monocyte composition in patients with stable HFrEF?
Observational (n=108)
Does cardiac resynchronization therapy normalize altered monocyte composition in patients with stable HFrEF?
Answers are grounded in this paper and cite their sources.
Cardiac resynchronization therapy may reverse the altered monocyte composition seen in patients with stable HFrEF, restoring it to levels observed in healthy controls.
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Ptaszyńska‐Kopczyńska et al. (2021) conducted an observational in Chronic Heart Failure with reduced Ejection Fraction (HFrEF) (n=108). Cardiac resynchronization therapy (CRT) vs. Volunteers without HFrEF was evaluated on Changes in monocyte compartment (p=0.003). Cardiac resynchronization therapy in patients with HFrEF normalized altered monocyte composition to levels observed in controls without HFrEF (P=0.003).
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