Why the study?
High-sensitivity assays have created new clinical challenges in differentiating post-exercise cardiac troponin elevation from pathological necrosis in chest pain patients.
How does serial cardiac troponin testing help differentiate exercise-induced troponin elevation from myocardial infarction in patients with post-exercise chest pain?
Design
Review
Key result
Marathon running induced high-sensitivity cardiac troponin T elevation above the myocardial infarction threshold in 100% of participants at 0 and 3 hours post-race, falling to 22% at 24 hours.
Authors
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Serial troponin testing may differentiate exercise-induced elevation from MI; leaves open prospective validation in symptomatic athletes.
How does serial cardiac troponin testing help differentiate exercise-induced troponin elevation from myocardial infarction in patients with post-exercise chest pain?
Understanding the distinct kinetics of exercise-induced cardiac troponin elevation helps clinicians differentiate benign physiological responses from acute myocardial infarction.
Baker et al. (2019) conducted a review in Exercise-induced cardiac troponin elevation (n=26). Marathon running vs. Baseline (pre-race) was evaluated on High-sensitivity cardiac troponin T (HS-cTnT) elevation above the 99th percentile URL (14 ng/L). Marathon running induced high-sensitivity cardiac troponin T elevation above the myocardial infarction threshold in 100% of participants at 0 and 3 hours post-race, falling to 22% at 24 hours.
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