Reduced left ventricular torsion (<0.59 degrees/cm) significantly increased the risk of hospitalization for worsening heart failure compared to relatively preserved torsion (HR 6.41).
Observational (n=91)
Double-blind
No
Does reduced LV torsion predict hospitalization for worsening heart failure in patients with non-ischemic dilated cardiomyopathy?
Reduced left ventricular torsion measured by 3D speckle-tracking echocardiography is a strong, independent predictor of hospitalization for worsening heart failure in patients with non-ischemic dilated cardiomyopathy.
Estimación del efecto: HR 6.41 (95% CI 2.19-18.83)
Tasa de eventos absoluta: 47% vs 7%
valor p: p=<0.001
BACKGROUND: Left ventricular (LV) torsion is a key parameter in cardiac function and predicts functional capacity (FC) more appropriately than LV ejection fraction (EF). We sought to investigate LV torsion as a marker of hospitalization for worsening heart failure (HF) in non-ischemic dilated cardiomyopathy (DCM) patients. METHODS AND RESULTS: (C-index: 0.85, P=0.02). CONCLUSIONS: The results demonstrated a clear relation between LV torsion and disease severity, suggesting that LV torsion has additional prognostic relevance in DCM patients.
Rady et al. (Sat,) conducted a observational in Non-ischemic dilated cardiomyopathy (n=91). Reduced LV torsion (<0.59 degrees/cm) vs. Relatively preserved LV torsion (>0.59 degrees/cm) was evaluated on Hospital admission for worsening heart failure (HR 6.41, 95% CI 2.19-18.83, p=<0.001). Reduced left ventricular torsion (<0.59 degrees/cm) significantly increased the risk of hospitalization for worsening heart failure compared to relatively preserved torsion (HR 6.41).