Key result
Reduced left ventricular torsion (<0.59 degrees/cm) significantly increased the risk of hospitalization for worsening heart failure compared to relatively preserved torsion (HR 6.41).
Why the study?
LV torsion predicts functional capacity better than LVEF, prompting investigation into whether it marks hospitalization for worsening HF in non-ischemic DCM.
Does reduced LV torsion predict hospitalization for worsening heart failure in patients with non-ischemic dilated cardiomyopathy?
Observational (n=91)
Double-blind
No
Does reduced LV torsion predict hospitalization for worsening heart failure in patients with non-ischemic dilated cardiomyopathy?
Reduced left ventricular torsion measured by 3D speckle-tracking echocardiography is a strong, independent predictor of hospitalization for worsening heart failure in patients with non-ischemic dilated cardiomyopathy.
May support LV torsion for HF risk stratification in non-ischemic DCM; hypothesis-generating and requires prospective validation.
BACKGROUND: Left ventricular (LV) torsion is a key parameter in cardiac function and predicts functional capacity (FC) more appropriately than LV ejection fraction (EF). We sought to investigate LV torsion as a marker of hospitalization for worsening heart failure (HF) in non-ischemic dilated cardiomyopathy (DCM) patients. METHODS AND RESULTS: (C-index: 0.85, P=0.02). CONCLUSIONS: The results demonstrated a clear relation between LV torsion and disease severity, suggesting that LV torsion has additional prognostic relevance in DCM patients.
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Rady et al. (2019) conducted an observational in Non-ischemic dilated cardiomyopathy (n=91). Reduced LV torsion (<0.59 degrees/cm) vs. Relatively preserved LV torsion (>0.59 degrees/cm) was evaluated on Hospital admission for worsening heart failure (HR 6.41, 95% CI 2.19-18.83, p=<0.001). Reduced left ventricular torsion (<0.59 degrees/cm) significantly increased the risk of hospitalization for worsening heart failure compared to relatively preserved torsion (HR 6.41).
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