Key result
Left ventricular torsion <0.61 degrees/cm predicted reduced functional capacity with high sensitivity and specificity (AUC 0.88), outperforming left ventricular ejection fraction.
Why the study?
Does left ventricular torsion measured by 3D speckle-tracking echocardiography correlate with peak oxygen uptake and predict reduced functional capacity in patients with dilated cardiomyopathy?
Cross-Sectional (n=45)
No
Does left ventricular torsion measured by 3D speckle-tracking echocardiography correlate with peak oxygen uptake and predict reduced functional capacity in patients with dilated cardiomyopathy?
Effect estimate: OR 0.05 (95% CI 0.01-0.19)
p-value: p=<0.001
Left ventricular torsion measured by 3D speckle-tracking echocardiography is a strong, independent predictor of functional capacity in patients with dilated cardiomyopathy, outperforming standard LVEF and strain measurements.
May support LV torsion assessment of functional capacity in dilated cardiomyopathy; extends speckle-tracking applications but leaves open prospective validation.
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Sveric et al. (2017) conducted a cross-sectional in Non-ischemic dilated cardiomyopathy (n=45). Left ventricular torsion assessment via 3D speckle-tracking echocardiography vs. Left ventricular ejection fraction (LV EF) was evaluated on Prediction of reduced functional capacity (peak VO2 <20 mL/kg/min) using LV torsion cut-off of 0.60 degrees/cm (OR 0.05, 95% CI 0.01-0.19, p=<0.001). Left ventricular torsion <0.61 degrees/cm predicted reduced functional capacity with high sensitivity and specificity (AUC 0.88), outperforming left ventricular ejection fraction.
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