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September 10, 2025Journal of Cardiovascular Development and DiseaseOpen Access

CMR-Derived Global Longitudinal Strain and Left Ventricular Torsion as Prognostic Markers in Dilated Cardiomyopathy

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Authors

AZAlexandru ZlibutMBMichael BietenbeckLALucia Agoşton-Coldea

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Overview

This prospective study confirms global longitudinal strain and left ventricular torsion as key prognostic markers in patients with dilated cardiomyopathy, suggesting enhanced risk stratification.

Key Points

  • CMR-derived GLS and LV torsion predict major adverse cardiovascular events in dilated cardiomyopathy patients.
  • DCM patients showed significantly reduced ejection fraction (35.1% vs. 65.2%, p < 0.001) compared to healthy controls.
  • Patients with GLS ≤ −8.6% exhibited a higher risk for adverse outcomes (HR: 1.09; p < 0.01), while reduced LV torsion also indicated increased risk (HR: 1.37; p < 0.01).
  • The presence of late gadolinium enhancement further stratified risk, reinforcing the value of myocardial deformation analysis in DCM evaluation.

Cite This Study

Zlibut et al. (2025) studied this question.

synapsesocial.com/papers/68c189e79b7b07f3a0613da4https://doi.org/10.3390/jcdd12090340
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