Polymer-supported radiopharmaceuticals: 131IMIBG and 123IMIBG

A new method has been developed that produces no-carrier-added 131IMIBG in ≥90% radiochemical yield and high chemical purity. Isolation and purification are simple involving just filtration and absorption and desorption onto a C18 Sep-Pak™ cartridge. No-carrier-added material should avoid the potential pharmacological side effects accompanying the current method of production. Copyright © 1999 John Wiley & Sons, Ltd.