A new method has been developed that produces no-carrier-added [131I]MIBG in ≥90% radiochemical yield and high chemical purity. Isolation and purification are simple involving just filtration and absorption and desorption onto a C18 Sep-Pak™ cartridge. No-carrier-added material should avoid the potential pharmacological side effects accompanying the current method of production.
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Hunter et al. (1999) studied this question.
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