Why the study?
Does medical therapy to lower systolic blood pressure by 10 mm Hg reduce cardiovascular events in individuals with hypertension?
Population
Individuals with hypertension
Design
Review
Key result
Every 10 mm Hg systolic blood pressure lowering with medical therapy reduces cardiovascular disease events by 20%, coronary heart disease by 17%, stroke by 27%, and heart failure by 28%.
Authors
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Supports BP lowering for CVD prevention in hypertension; leaves open optimal targets by subgroup.
Does medical therapy to lower systolic blood pressure by 10 mm Hg reduce cardiovascular events in individuals with hypertension?
Lowering systolic blood pressure by 10 mm Hg significantly reduces the risk of major cardiovascular events, reinforcing the importance of BP control in CVD prevention.
Karmali et al. (2017) conducted a review in Hypertension. Blood pressure lowering medical therapy was evaluated on Cardiovascular disease events. Every 10 mm Hg systolic blood pressure lowering with medical therapy reduces cardiovascular disease events by 20%, coronary heart disease by 17%, stroke by 27%, and heart failure by 28%.
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