Tissue Doppler imaging-derived Aa-IV intervals correlated significantly better with fetal ECG PR intervals (R2 = 0.15, p < 0.0001, mean bias 8.0 ms) than did pulse-wave Doppler-derived AV intervals.
Cohort (n=131)
No
Does tissue Doppler imaging correlate better with fetal ECG PR intervals than pulse-wave Doppler in assessing fetal atrioventricular time intervals?
Tissue Doppler imaging-derived Aa-IV intervals track fetal ECG PR intervals more closely than pulse-wave Doppler methods, establishing it as the preferred ultrasound method for assessing fetal AV conduction.
Estimación del efecto: R2 = 0.15
valor p: p=<0.0001
OBJECTIVE: To establish gestational age-specific reference values of normal fetal atrioventricular (AV) time interval by spectral tissue Doppler imaging (TDI) and pulse-wave Doppler (PD) methods, and to assess their correlation with signal-averaged fetal PR intervals (ECG). DESIGN: Cohort study. SETTING: Tertiary centre for fetal cardiology. PATIENTS AND MEASURES: 131 pregnant women between 14 and 42 weeks' gestation underwent 196 fetal echocardiograms and 158 fetal ECG studies. TDI-derived AV intervals were measured as the intervals from atrial contraction (Aa) to isovolumic contraction (IV) and from Aa to ventricular systole (Sa) at the right ventricular free wall. PD-derived AV intervals were measured from simultaneous left ventricular inflow/outflow (in/out) and superior vena cava/aorta (V/AO) recordings. RESULTS: Measurements were possible by ECG in 61%, by TDI in 100%, by in/out in 100% and by V/AO in 97% of examinations. Aa-IV correlated significantly better with PR intervals (y = 0.67x + 38.29, R(2) = 0.15, p < 0.0001, mean bias 8.0 ms) than did in/out (R(2) = 0.10, p = 0.002, bias 18.7 ms) and V/AO (R(2) = 0.06, p = 0.02, bias 12.4 ms). Gestational age and AV intervals were positively correlated with all imaging modalities (R(2) = 0.19-0.31, p < 0.0001). CONCLUSION: This study showed the feasibility of fetal AV interval measurements by TDI, and established gestational age-specific reference data. TDI-derived Aa-IV intervals track ECG PR intervals more closely than PD-derived AV intervals and thus should be used as the ultrasound method of choice in assessing fetal AV conduction.
Nii et al. (Wed,) conducted a cohort in Normal fetal cardiac anatomy, function and rhythm (n=131). Tissue Doppler imaging (TDI) vs. Pulse-wave Doppler (PD) and fetal ECG was evaluated on Correlation of TDI-derived Aa-IV intervals with ECG PR intervals (R2 = 0.15, p=<0.0001). Tissue Doppler imaging-derived Aa-IV intervals correlated significantly better with fetal ECG PR intervals (R2 = 0.15, p < 0.0001, mean bias 8.0 ms) than did pulse-wave Doppler-derived AV intervals.