Reversible modification of human plasma low density lipoproteins toward triglyceride-rich precursors. A mechanism for losing excess cholesterol esters.

Puntos clave

• The study investigates how human plasma low density lipoproteins can be modified into triglyceride-rich precursors to reduce excess cholesterol esters.
• In vitro incubation of low density lipoproteins with very low density lipoproteins.
• Analysis of resulting lipoprotein modifications after treatment with lipoprotein lipase.
• Human plasma low density lipoproteins are successfully modified into triglyceride-rich lipoprotein precursors.
• The modification is reversible and may assist in reducing cholesterol ester levels in plasma.