What question did this study set out to answer?

The study investigates how human plasma low density lipoproteins can be modified into triglyceride-rich precursors to reduce excess cholesterol esters.

June 1, 1982Journal of Biological ChemistryOpen Access

Reversible modification of human plasma low density lipoproteins toward triglyceride-rich precursors. A mechanism for losing excess cholesterol esters.

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Authors

RDRichard J. DeckelbaumColumbia University SES EisenbergHadassah Medical Center YOY OschryTel Aviv University

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Implication

Demonstrates lipid modification in low density lipoproteins, suggesting a mechanism for cholesterol ester reduction.

Key Points

The study investigates how human plasma low density lipoproteins can be modified into triglyceride-rich precursors to reduce excess cholesterol esters.
In vitro incubation of low density lipoproteins with very low density lipoproteins.
Analysis of resulting lipoprotein modifications after treatment with lipoprotein lipase.
Human plasma low density lipoproteins are successfully modified into triglyceride-rich lipoprotein precursors.
The modification is reversible and may assist in reducing cholesterol ester levels in plasma.

Cite This Study

Deckelbaum et al. (1982) studied this question.

synapsesocial.com/papers/6a69d2bd327391d1bb1a5f07 https://doi.org/10.1016/s0021-9258(20)65171-7

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Reversible modification of human plasma low density lipoproteins toward triglyceride-rich precursors. A mechanism for losing excess cholesterol esters.

Discussion

Member takes

Implication

Key Points

Cite This Study

Reversible modification of human plasma low density lipoproteins toward triglyceride-rich precursors. A mechanism for losing excess cholesterol esters.

Discussion

Member takes

Implication

Key Points

Cite This Study

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