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Where the evidence has converged — synthesized from landmark RCTs and meta-analyses across cardiology.
Does dapagliflozin vs placebo affect OUT:cv-death-or-worsening-hf in Heart Failure with Reduced Ejection Fraction?
1 studies (4,744 patients, 1 RCTs) provide moderate-certainty evidence for benefit of dapagliflozin for Composite of worsening HF or cardiovascular death in Heart Failure with Reduced Ejection Fraction.
1 RCTs · 4,744 ptsDoes oral anticoagulation vs placebo improve All-Cause Mortality in Atrial Fibrillation?
21 studies (1,389,742 patients) provide low-certainty evidence for benefit of oral anticoagulation for All-Cause Mortality in Atrial Fibrillation.
1,389,742 ptsDoes exenatide vs placebo improve All-Cause Mortality in Diabetes Mellitus, Non-Insulin-Dependent?
5 studies (44,256 patients) provide low-certainty evidence for benefit of exenatide for All-Cause Mortality in Diabetes Mellitus, Non-Insulin-Dependent.
44,256 ptsDoes ticagrelor vs clopidogrel improve Myocardial Infarction Hospitalization in Acute Coronary Syndrome?
3 studies (41,464 patients) provide low-certainty evidence for benefit of ticagrelor for Myocardial Infarction Hospitalization in Acute Coronary Syndrome.
41,464 ptsDoes dabigatran vs warfarin improve outcomes in HEART-VALVE, MECHANICAL?
3 studies (0 patients) provide low-certainty evidence for benefit of dabigatran for Ventricular Arrhythmia in HEART-VALVE, MECHANICAL.
Does amiodarone vs placebo improve outcomes in Atrial Fibrillation?
10 studies (49,075 patients) provide low-certainty evidence against benefit of amiodarone for Myocardial Infarction Hospitalization in Atrial Fibrillation.
49,075 ptsDoes immune checkpoint inhibitors vs placebo improve outcomes in cancer therapy-related cardiovascular toxicity?
3 studies (324 patients) provide low-certainty evidence against benefit of immune checkpoint inhibitors for Cardiac Index in cancer therapy-related cardiovascular toxicity.
324 ptsDoes asparaginase vs placebo improve outcomes in L2 Acute Lymphoblastic Leukemia?
4 studies (221 patients) provide low-certainty evidence against benefit of asparaginase for Myocardial Infarction Hospitalization in L2 Acute Lymphoblastic Leukemia.
221 ptsDoes dipyridamole vs placebo improve Left Ventricular Ejection Fraction in Aortic Valve Stenosis?
2 studies (30 patients) provide low-certainty evidence against benefit of dipyridamole for Left Ventricular Ejection Fraction in Aortic Valve Stenosis.
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