Allergic rhinitis (AR) is a common noninfectious chronic inflammatory disease of the nasal mucosa mediated by Immunoglobulin E (IgE). Currently, the diagnosis of AR mainly relies on a typical history of allergies, clinical symptoms and signs, skin prick tests, nasal provocation tests, and serum specific IgE detection. Nasal secretion cytology, as a method that directly reflects the inflammatory status in the nasal cavity, also plays a significant role in the diagnosis and treatment of AR. This review summarizes and discusses the role of nasal cytology in the diagnosis and treatment of AR, based on systematically selected articles from the PubMed database, with the aim of advancing this method and its clinical application. Nasal cytology holds significant potential in revolutionizing the diagnosis and treatment of AR. Addressing the current challenges and limitations through standardization, validation studies, and integration of new technologies will pave the way for its widespread adoption and ultimately contribute to precision medicine.
Song et al. (Fri,) studied this question.