Supplementary Figure 9 from Defining the Ovarian Cancer Precancerous Landscape through Modeling Fallopian Tube Epithelium Reprogramming Driven by Extracellular Vesicles | Synapse
August 4, 2025
Supplementary Figure 9 from Defining the Ovarian Cancer Precancerous Landscape through Modeling Fallopian Tube Epithelium Reprogramming Driven by Extracellular Vesicles
Key Points
OVCAR3 extracellular vesicles significantly downregulate PAX2 expression in the epithelium.
The study suggests that changes in PAX2 may play a role in ovarian cancer development.
Modeling fallopian tube epithelium helps in understanding the precancerous landscape of ovarian cancer.
Findings indicate that extracellular vesicles could be crucial in early cancer detection and intervention.