January 1, 2025Open Access

19F Solid-State Nuclear Magnetic Resonance as a tool to study the bioaccumulation of per-and polyfluoroalkyl substances in murine tissue samples

RNRachel NeitaMemorial University of Newfoundland SKSophie KiefteMemorial University of Newfoundland HAHaley AdamsMemorial University of Newfoundland

Key Points

PFAS accumulation in murine tissues has been confirmed, emphasizing their environmental persistence.
Findings show that PFAS are linked to potential health risks like kidney and liver disease, highlighting urgent health concerns.
Assessment using solid-state nuclear magnetic resonance provides detailed insights into tissue bioaccumulation of PFAS.
Understanding PFAS bioaccumulation is crucial to address environmental and health issues related to their persistence.

Abstract

Per-and polyfluoroalkyl substances (PFAS) are known to be persistent in the environment and are associated with adverse health effects including kidney and liver disease and developmental toxicity. While PFAS are...

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