Abstract Study Objectives Weekend catch-up sleep (WCUS) has been identified as a potential compensatory alternative for weekday sleep deprivation. While previous studies have highlighted the positive association between the appropriate duration of WCUS and health-related quality of life (HRQoL), the precise estimation has not been much conducted. Moreover, considering that sex and chronotype may specifically influence the association, a more flexible and detailed approach is required. Methods We mainly focused on 15,038 healthy adults without severe medical conditions from the 7th (2016–2018) Korea National Health and Nutrition Examination Survey and used a generalized additive model to investigate non-linear associations between WCUS and HRQoL. In addition, we conducted subgroup analyses by sex and chronotype to understand the associations from various perspectives. Results In the results with the total subjects, we found a significant non-linear association of a supine S-shape. In this association, the range of WCUS that could significantly improve HRQoL was 0.49–2.13 hours, and the corresponding odds ratio (OR) was 1.11–1.26. In addition, we conducted subgroup analyses using sex and chronotype. In the sex subgroup analyses, no significant results were observed in males, whereas females showed a significantly non-linear supine S-shaped association and the significant range of WCUS was 0.47–2.10 hours (OR=1.14–1.34). After chronotype was additionally considered, only the intermediate-type and evening-type females showed significant non-linear associations. Conclusions Tailored sleep interventions based on individual characteristics and specific WCUS durations may serve as an effective strategy to improve HRQoL.
Oh et al. (Thu,) studied this question.
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