Congenital diaphragmatic hernia (CDH) continues to be a substantial cause of neonatal mortality, with right-sided CDH frequently being linked to a poor prognosis than left-sided defects. We present two cases of right CDH that serve as an illustration of the wide range of clinical outcomes that may result from this condition. The first case involved a syndromic male neonate who was born with inadequate respiratory effort and necessitated aggressive resuscitation. He was diagnosed with right CDH and left tension pneumothorax, two life-threatening comorbidities that ultimately resulted in his death. In contrast, the second case involved a healthy female neonate who presented with respiratory distress as a result of an isolated right CDH. In the aftermath of the diaphragmatic defect's surgical correction, her right lung recovered, and she achieved a favourable outcome. The clinical course of right CDH is influenced by a variety of factors, such as the extent of the defect, the presence of a hernia sac, liver herniation, ipsilateral lung volume, and suspected genetic syndromes. In comparison to left-sided lesions, the risk of mortality for right CDH is higher, despite the availability of sophisticated perioperative care. It is essential to identify CDH in neonates with respiratory symptoms at an early stage in order to expedite surgical intervention and facilitate stabilisation.
Ong et al. (Thu,) studied this question.