Background: In Ayurveda, Pandu Roga is one of the major disease described in classical Ayurvedic texts, presents with symptoms similar to Iron Deficiency Anaemia (IDA) such as pallor, fatigue, anorexia. In India Anaemia affects estimated 50% of the population. Conventional iron supplements, although effective, are often accompanied by gastrointestinal and other adverse effects. Traditional formulations Gudanagaradi Gutika and Phalatrikadi Kwatha offer potential safer alternatives based on their hematopoietic and digestive stimulant properties. This study aims to compare these two Ayurvedic interventions for managing Pandu Roga . Objective: To evaluate and compare the clinical efficacy and safety of Gudanagaradi Gutika and Phalatrikadi Kwatha in the management of Pandu Roga (Iron Deficiency Anaemia). Methods: A single-centered, open-labelled, parallel comparative clinical trial will be conducted on 60 patients (aged 25–45 years) diagnosed with Pandu Roga. Participants will be randomized into two groups (n = 30 each).GroupA(Intervention),Gudanagaradi Gutika (500 mg twice daily) and Group-B (Comparator),Phalatrikadi Kwatha (50 ml twice daily).The treatment will continue for 28 days. Outcome assessments include subjective parameters (pallor, anorexia, etc.) and objective parameters (Hemoglobin levels, Serum Ferritin etc). Follow-up evaluations on days 7th, 14th, 21st, 28th during treatment and days 42nd and 56th post-treatment. Statistical significance is set at p < 0.05. Expected Results: Both formulations will anticipated to improve clinical symptoms and hematological parameters; however, Gudanagaradi Gutika is hypothesized to yield a superior efficacy because of its hematopoietic and digestive stimulant components.
Pooja Sharma (Wed,) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: