Dushta Vrana (chronic or infected wound) is a frequently encountered condition in surgical practice and can significantly compromise a patient's health due to complications like slough, infection, and foreign bodies, all of which interfere with the natural wound healing process. A clean, uncontaminated wound in a healthy body heals more efficiently with minimal scarring, whereas a contaminated wound requires proper management to initiate healing. The primary therapeutic goal in the treatment of Dushta Vrana is to convert it into a Shuddha Vrana, thereby facilitating the process of Ropana (wound healing). This clinical study was undertaken to evaluate the efficacy of Tiladi Lepa and its gel-based formulation in managing Dushta Vrana. A total of 40 clinically diagnosed patients were randomly divided into two groups of 20 patients each. Group A received local application of Tiladi Lepa, while Group B was treated with the gel form of Tiladi Lepa. The evaluation was carried out using both subjective parameters (pain, burning sensation, itching) and objective parameters (wound size, discharge, odor, and granulation tissue formation). Both groups showed statistically significant improvement (P < 0.05); however, the Gel form of Tiladi Lepa (Group B) demonstrated relatively better outcomes in most clinical parameters. Although the statistical difference between the two groups was not highly significant, the comparative analysis of individual parameters and the overall response suggests that the gel formulation of Tiladi Lepa offers superior Ropana (healing) properties compared to the traditional Tiladi Lepa. Thus, the gel form may be considered more effective in promoting wound healing in cases of Dushta Vrana.
Kumar et al. (Wed,) studied this question.