What type of study is this?

This is a Experimental Study study.

September 17, 2025

Fast 3D cardiac extracellular volume mapping and cine imaging via continuous free-breathing acquisition with mid-scan contrast agent injection

Key Points

Three-dimensional cardiac ECV maps can be created in just 20 minutes, overcoming traditional challenges of respiratory motion during imaging.
By injecting contrast agents during the scan, the study reduces total scan time significantly, improving patient experience and operational efficiency.
Continuous acquisition using inversion recovery spoiled gradient-echo optimizes data collection and enhances image clarity and resolution.
This new imaging approach integrates both ECV mapping and cine imaging into a singular process, demonstrating its potential for clinical applications.

Abstract

Motivation: Three-dimensional cardiac extracellular volume (ECV) mapping and cine imaging are challenging due to respiratory and cardiac motions. Existing ECV mapping methods wait at least 10-minutes after contrast agent administration which increases the total scan time. Goal(s): To develop a time-efficient method for free-breathing 3D cardiac ECV mapping and cine imaging. Approach: Data was acquired continuously using inversion recovery spoiled gradient-echo (IR-SPGR) with mid-scan contrast agent administration. The Linear Tangent Space Alignment (LTSA) model was used for image reconstruction. Results: Three-dimensional cardiac ECV maps and cine images were obtained in a 20-minute free-breathing scan with contrast agent injection in between. Impact: We propose a highly time-efficient, free-breathing 3D cardiac imaging method that integrates ECV mapping and cine imaging in a single scan with mid-scan contrast agent injection.

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Fast 3D cardiac extracellular volume mapping and cine imaging via continuous free-breathing acquisition with mid-scan contrast agent injection

Key Points

Abstract

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