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This is a Experimental Study study.

September 17, 2025

Improved-Contrast Accelerated 3D Cones LGE using Cardiac Binning and Keyhole-Filtered View Sharing

Key Points

Accelerated 3D Cone LGE MRI significantly enhances myocardial scar differentiation from surrounding tissues, improving treatment planning.
Keyhole-filtered view-sharing reconstruction yielded better image sharpness and contrast in scans, achieving high-quality results.
In-vivo imaging conducted on infarcted pig hearts highlights the effectiveness of this technique in real-time cardiac interventions.
Overall, the findings indicate that faster imaging methods can lead to more precise and effective cardiac treatments.

Abstract

Motivation: To enable faster, high-resolution late gadolinium enhancement (LGE) MRI for detailed myocardial scar visualization, we developed a 3D cone trajectory approach to achieve faster scans with enhanced image quality. Goal(s): To reduce scan time and improve image sharpness and contrast in 3D Cones LGE MRI, focusing on the clear differentiation of scar tissue. Approach: We implemented a keyhole-filtered view-sharing reconstruction technique with a 3D Cone sequence to accelerate LGE imaging within in-vivo infarcted pig hearts. Results: Fast 3D Cone LGE with keyhole-filtered view-sharing reconstruction achieved enhanced scar contrast and edge sharpness, as confirmed by improved differentiation between scar, myocardium, and blood pool. Impact: This accelerated imaging enables high-quality myocardial scar visualization, improving pre-treatment or real-time intra-treatment planning for MRI-guided cardiac arrhythmia interventions.

Improved-Contrast Accelerated 3D Cones LGE using Cardiac Binning and Keyhole-Filtered View Sharing

Key Points

Abstract

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