Abstract The Human papillomavirus (HPV) is a highly prevalent virus transmitted through intimate skin-to-skin contact and is extensively distributed globally, through sexual activity. It comprises over 200 related viral types, some of which are sexually transmitted and are associated with warts or specific forms of cancer. High-risk HPV strains, such as HPV 16 and 18, are responsible for the majority of cervical carcinomas as well as other cancers of the anogenital and oropharyngeal regions. More than 75% of sexually active individuals will encounter this infection during their lifetime, with the majority of sexually active persons becoming exposed at some point (CDC, 2023). Our objectives are to enhance awareness and comprehension of HPV transmission, prevention, and its association with cancer, while promoting HPV vaccination among young adults aged 18-25Also, to increase HPV vaccination rates by 20% within one year through targeted educational initiatives and routine screening to diminish HPV-related cancers. The TdV program was initiated in El Paso County in August 2014 and was subsequently expanded in 2019 to include Brewster, Culberson, Hudspeth, and Presidio counties. Our methodology includes eligibility criteria specify individuals aged 9 to 45 years who have not completed the HPV vaccine series and who are either uninsured or underinsured, with self-reported residency in Texas. The third phase, known as TdV3, has been active since 2024. This phase expands the original program by broadening its scope to additional border counties while preserving collaborations with all 175 community sites within the network. New strategic initiatives comprise: 1) culturally tailored HPV education; 2) complementary HPV vaccines; 3) patient navigation and tracking to ensure adherence to follow-up doses and completion of the vaccine series; and 4) culturally appropriate school-based vaccination initiatives (SBVI) and peer education programs. Our result shows that since the program's inception, a total of 4,564 individuals have been recruited, 5,621 vaccines have been administered, and 124,207 individuals have been reached through social media. In conclusion, the program continues to expand its collaborations throughout Texas to increase HPV vaccination uptake and reduce the impact of HPV-associated cancers through a combination of traditional outreach methods and innovative social media strategies. Citation Format: Grace Otitoju, Sonia Escamilla, Pracheta Matharasi, Jennifer Molokwu. Tiempo de vacunarte: A community human papillomavirus (HPV) vaccination program (2014-2025) funded by CPRIT (PP140211, PP190058, PP240014) abstract. In: Proceedings of the 18th AACR Conference on the Science of Cancer Health Disparities; 2025 Sep 18-21; Baltimore, MD. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2025;34(9 Suppl):Abstract nr B027.
Otitoju et al. (Thu,) studied this question.