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September 23, 2025Open Access

Double versus standard dose of tamsulosin with solifenacin for management of ureteral stent related symptoms

Key Points

Double dosing tamsulosin showed enhanced relief of stent-related symptoms compared to standard dosing, improving patient comfort significantly.
The primary measure indicated that patients on the double dose experienced a reduction in symptoms, with improvement rates surpassing 50%.
Assessment involved a randomized, controlled trial to evaluate symptom management in patients with ureteral stents using tamsulosin and solifenacin.
The findings may highlight the need for re-evaluation of dosing strategies in pharmacological treatments for ureteral stent discomfort.

Abstract

Background Ureteral stents are commonly used to ensure adequate drainage of the upper urinary tract in the presence, or anticipated occurrence, of ureteral obstruction. However, stent-related symptoms are frequent and represent a significant source of morbidity. Although several pharmacological treatment options are currently available, symptom relief remains often incomplete. In an effort to achieve better control of stent-related symptoms, we evaluated the efficacy of dose doubling in two commonly used drug combinations that have demonstrated symptomatic benefits in this context.

Double versus standard dose of tamsulosin with solifenacin for management of ureteral stent related symptoms

Key Points

Abstract

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