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Mesial temporal lobe epilepsy is the most common type of drug-resistant epilepsy, with hippocampus sclerosis (HS) being its most common pathology. Anterior temporal lobectomy is the most common surgical strategy for these patients, many still suffer from seizures post-surgery, which may relate to their extensive brain network damage. 18F-FDG-PET is sensitive to metabolic changes in the epileptogenic zone. DTI can assess the integrity of white-matter tracts. In this study, we investigated the changes in glucose uptake, white-matter tracts, and their differences in brain networks of MR-HS versus MR-negative patients using simultaneous PET/MR, and studied if these changes coincide topographically.
Huang et al. (Wed,) studied this question.
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