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At high field, magnetization transfer (MT) imaging suffers from the high specific absorption ratio (SAR) issue due to the usage of high power off-resonance MT RF pulses, and on-resonance saturation caused by B0 field inhomogeneity. At ultra-low-field (ULF), the low SAR and low absolute B0 inhomogeneity (in Hz) greatly facilitates the application of strong and versatile MT pulses without the confounding on-resonance saturation in practice. We demonstrate brain MT imaging at ULF first the first time using a 0.055 Tesla MRI platform with an extremely low SAR.
Su et al. (Wed,) studied this question.