Rapid PD, T2, and T2* Mapping with 2in1-RARE-EPI and Model-Based Reconstruction in Multiple Sclerosis

One obstacle of established quantitative resonance imaging methods is the excessive scan time. This study examines the use of radially-sampled 2in1-RARE-EPI in conjunction with model-based reconstruction methods for accelerated and simultaneous PD, T2, and T₂^* mapping. We demonstrate that this approach facilitates a substantial decrease in acquisition time (01: 40 vs. 07: 12 min) of 2in1-RARE-EPI without impairing the quality of the parametric maps. Our patient data demonstrate the applicability of model-based reconstructed 2in1-RARE-EPI for T2 and T₂^* mapping of multiple sclerosis lesions.