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Susceptibility separation may distinguish iron and myelin in multiple sclerosis (MS) lesions, but little work has been done on longitudinal changes. Twenty MS subjects were followed for 14 months to investigate para and diamagnetic changes independently using susceptibility separation in comparison to transverse relaxation and susceptibility mapping. Susceptibility separation provided distinction between myelin and iron events, offering more insight into MS lesion evolution.
Zhu et al. (Wed,) studied this question.
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