July 8, 2024Open Access

Metformin induces tumor immunogenic cell death in ovarian cancer by activating AMPK pathway

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Abstract

Inducing immunogenic cell death (ICD) process may be an important antitumor strategy in ovarian cancer (OC). Metformin (Met) has been shown to have antitumor effects in OC, but whether it mediates the ICD to inhibit OC process is unclear. Human OC cell lines (SKOV3 and A2780) were treated with Met. Dendritic cell (DC) and CD8

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Chen et al. (Mon,) studied this question.

synapsesocial.com/papers/68e60f70b6db6435875a2ddd https://doi.org/https://doi.org/10.1016/j.tranon.2024.102052

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