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Introduction: Lignocaine and Bupivacaine are the drugs used for long time. In this setting one of the newer drug Ropivacaine has emerged and which is available as hyperbaric and isobaric solution. It is used mainly for epidural, subarachnoid block. Ropivacaine was chosen as 0.75% hyperbaric solution for this study. Dexmedetomidine was chosen as an additive to potentate the effects of local anaesthetics. To compare the clinical effects of intra thecal ropiva Objectives: caine and ropivacaine with dexmedetomidine with respect to - 1. Onset of sensory and motor blockade 2. Hemodynamic stability 3. Duration of sensory and motor blockade 4. Observed any side effects. Material & Methods: A prospective randomized clinical study is conducted on 50 patients of ASA grade 1, 2 and 3 belonging to the age group of 18-45 years undergoing lower abdominal surgery under spinal anesthesia to study the comparison of 0.75% hyperbaric ropivacaine (3ml) with dexmedetomidine as adjuvant vs 0.75% hyperbaric ropivacaine (3ml) without adjuvant intrathecally in lower limb surgery. Two group were divided. Group R received intrathecal injection of 0.75% hyperbaric ropivacaine(3ml) and Group D received intrathecal injection of 0.75% hyperbaric Ropivacaine (3ml). + Dexmedetomidine 3 g. It was found th Results: at intrathecal hyperbaric ropivacaine in this study produces T7 - T8 level of sensory blockade with adequate motor blockade for lower abdominal surgeries and patients were hemodynamically stable. Group D patients early onset of sensory and motor blockade and delayed recovery from sensory blockade and motor blockade noted with prolongation of total duration of post operative analgesia and patients were more comfortable (free of anxiety) in this group D than group R. Hyperbaric Ropivacaine is a safe anaesthetic of choice for intra thecal use i Conclusion: n abdominal surgery cases, (ASA I & II) and by adding dexmedetomidine we get early onset of sensory as well as motor block and prolonged duration of motor block and total time of post-operative analgesia.
Marfatia et al. (Sat,) studied this question.