May 21, 2024Open Access

Dual neutrophil subsets exacerbate or suppress inflammation in tuberculosis via IL-1β or PD-L1

EDEmilie DozUniversité de Tours BBBadreddine BounabUniversité de Tours FCFlorence CarrerasUniversité de Tours

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Abstract

Neutrophils can be beneficial or deleterious during tuberculosis (TB). Based on the expression of MHC-II and programmed death ligand 1 (PD-L1), we distinguished two functionally and transcriptionally distinct neutrophil subsets in the lungs of mice infected with mycobacteria. Inflammatory [MHC-II

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