Formulation and Evaluation of Anti-inflammatory Ointment Containing Moringa oleifera Leaves Extract

It is common knowledge that the body uses inflammation as a natural defense against infection and to heal tissue damage. It is possible to link the anti-inflammatory properties of flavonoids to their suppression of the enzyme’s lipoxygenase and cyclooxygenase. The primary goal of the research was to create and assess an anti-inflammatory ointment with flavonoids of Moringa oleifera leaf extract. With valuable pharmacological actions like as anti-asthmatic, anti-diabetic, hepatoprotective, anti-inflammatory, anti-fertility, anti-cancer, anti-microbial, and antioxidant properties, this plant is widely utilized as a nutritional herb. Chemicals such as cetostearyl alcohol, hard paraffin, liquid paraffin, and wool fat were utilized in addition to Moringa oleifera leaf extract. The formulation is made with the appropriate technique and evaluated for spreadability, extrudability, washability, pH, color, smell, texture, and stability. Smooth, non-irritating, and skin-compatible prepared ointment. The suitability of the approach for the production of ointments was demonstrated by the physical evaluation of ointment preparations using extract of Moringa oleifera leaves. According to the study's findings, it serves as a substitute for anti-inflammatory medications that are just synthetic or chemical. These results confirm the M. oleifera plant's historic use as a successful treatment for illnesses and conditions linked to inflammation.