April 23, 2024Open Access

Effects of dexmedetomidine on renal function after cardiac surgery for infective endocarditis: An interim analysis of a randomized controlled trial

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Abstract

Patients undergoing cardiac surgery for infective endocarditis (IE) are at a high risk of postoperative acute kidney injury (AKI) owing to heightened systemic inflammation. Therefore, we aimed to investigate the effect of dexmedetomidine on postoperative AKI in patients who underwent cardiac surgery for IE.

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Ham et al. (Tue,) studied this question.

synapsesocial.com/papers/68e6df9ab6db64358765b525 https://doi.org/https://doi.org/10.1016/j.asjsur.2024.04.028

Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

1Subgroup analysis and other (mis)uses of baseline data in clinical trials2000 · 1,178 citations
2Dexmedetomidine suppresses proinflammatory mediator production in human whole blood in vitro2013 · 47 citations
3Dexmedetomidine and acute kidney injury following cardiac surgery in pediatric patients—An updated systematic review and meta-analysis2022 · 13 citations
4Proposed Modifications to the Duke Criteria for the Diagnosis of Infective Endocarditis2000 · 4,023 citations

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