The association between different physical activity (PA) patterns and cardiometabolic index (CMI) in US adult population from NHANES (2007–2016)

Highlights•Regularly active individuals reap significant cardiometabolic index (CMI) reduction, as opposed to weekend warriors and insufficiently active individuals.•Weekend warriors do not achieve equivalent CMI reduction as regularly active individuals.•A total of 330 min of physical activity per week yields favorable CMI reduction in non-inactive individuals.AbstractBackgroundPhysical activity (PA) is widely recommended for preventing and combating obesity, but the most effective PA pattern for treating obesity remains unclear. Cardiometabolic index (CMI), derived from waist height ratio and triglycerides to high-density lipoprotein-cholesterol ratio, is a novel indicator for evaluating obesity. However, the relationship between different PA patterns and CMI remains unelucidated.ObjectiveThis study aimed to explore the association between different PA patterns and CMI in U.S. adults.MethodsParticipants with complete information in CMI, PA patterns, and other covariates in the National Health and Nutrition Examination Survey database (2007–2016) were included in this study. Multivariate linear regression models were utilized to explore the relationship between PA patterns and CMI. Moreover, stratified analyses, interaction tests and restricted cubic spline (RCS) regression analysis were used to investigate the stability and nonlinearity of the association, respectively.ResultsA total of 16,442 adults were included in this study. After adjusting for all potential covariates, only the regularly active group was significantly associated with CMI reduction (β = −0.13, 95% CI: 0.19 to −0.07, P 60, with higher education level, and who are current drinkers. Furthermore, RCS analysis indicated that total PA in a week was significantly, nonlinearly associated with CMI in non-inactive adults, and that a total of PA more than 330 min can reap favorable CMI reduction.ConclusionBeing regularly active is associated with significant CMI reduction, while being weekend warriors and insufficiently active do not achieve equivalent benefits. For non-inactive individuals, engaging in PA for more than 330 min weekly helps to reduce CMI effectively.