December 4, 2025

Intraventricular Hemorrhage and Survival, Multimorbidity, and Neurodevelopment

Key Points

Survival rates are significantly affected by the presence of intraventricular hemorrhage in preterm infants, impacting their overall health.
Key findings indicate that intraventricular hemorrhage correlates with neurodevelopmental outcomes at 2 years of age in infants born very preterm.
Assessment of intraventricular hemorrhage trends reveals its critical role in long-term development among extremely preterm infants.
Long-term consequences of intraventricular hemorrhage remain uncertain, highlighting a need for continuous monitoring in clinical settings.

Abstract

( JAMA Network Open . 2025;8(1):e2452883. doi: 10.1001/jamanetworkopen.2024.52883) Intraventricular hemorrhage (IVH), a condition involving bleeding into the brain’s ventricular system, is a serious concern among infants born very preterm. Historically, severe IVH (grades 3 and 4) has been associated with increased risks of neurodevelopmental impairment (NDI), yet the full extent of long-term consequences, especially for milder cases (grades 1 and 2), remains unclear. The study aims to understand trends in IVH diagnosis and the association of IVH with survival and NDI at 2 years of age in a contemporary population of extremely preterm infants.

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Intraventricular Hemorrhage and Survival, Multimorbidity, and Neurodevelopment

Key Points

Abstract

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