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This research examines the relationship between platelet counts and prognosis in heart failure with mildly reduced ejection fraction.

December 9, 2025Open Access

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Platelet counts and prognosis in heart failure with mildly reduced ejection fraction: Results from a large-scaled registry

JDJonas DuddaHeidelberg University MBMichael BehnesHeidelberg University KWKathrin WeidnerHeidelberg University

Key Points

This research examines the relationship between platelet counts and prognosis in heart failure with mildly reduced ejection fraction.
Analyzed patient data from a large-scale registry
Assessed platelet counts in relation to prognosis
Measured all-cause mortality rates over 30 months
Platelet counts <50/nL and 50-<100/nL associated with increased risk of mortality
Findings based on hospitalized patients with HFmrEF
Increased mortality risk noted at 30 months of follow-up

Abstract

In patients hospitalized with HFmrEF, platelet counts of <50/nL and 50- < 100/nL were independently associated with an increased risk of all-cause mortality at 30 months.

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Platelet counts and prognosis in heart failure with mildly reduced ejection fraction: Results from a large-scaled registry

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