Divide and Correlate: Mapping Electronic Correlations in Proteins via Local Cut-Wise Reconstruction

Key Points

• The aim is to develop a method for quantifying electronic correlations in proteins, specifically insulin.
• Introduced a scalable method for analyzing electronic correlations.
• Utilized mutual information to characterize interactions.
• Employed a local cut-wise strategy to assess locality and decay of correlations.
• Quantified significant interatomic and inter-residue interactions in insulin.
• Demonstrated the effectiveness of the method in mapping electronic correlations.