ABSTRACT Wearable biosensors are reshaping personalized healthcare by offering real‐time and noninvasive monitoring of important physiological biomarkers. Rapid developments in microfluidic systems, electrochemical sensing, and liquid crystal technologies have enabled flexible devices that reliably collect biofluids and support sensitive on‐body measurements. This review brings together recent progress in these fields and explains how their combined use improves analytical performance, strengthens signal quality, and expands the range of measurable biomarkers. Advances in machine learning that support data interpretation and promote intelligent operation are also examined. Key challenges remain, including long‐term stability, variations in biofluid composition, and the need for scalable fabrication. This review outlines key opportunities for future research and provides a cohesive perspective on the scientific and engineering directions needed to realize clinically meaningful and commercially viable wearable diagnostic systems.
Esfandiar et al. (Thu,) studied this question.