Esophageal nerve sheath tumors are the least common type of esophageal submucosal tumors, with fewer than 60 cases reported in the literature. 1 These tumors typically occur as a solitary lesion in individuals aged 40–70, with a slight female predominance 2 and possible links to genetic syndromes such as neurofibromatosis type 2. 3 Due to their rarity, they are often poorly recognized clinically and misdiagnosed prior to surgery. We present a rare case of esophageal nerve sheath tumor, diagnosed on esophagogastroduodenoscopy in a 46-year-old male who presented with chronic iron deficiency anemia. The patient was successfully treated with endoscopic submucosal dissection. This case highlights diagnostic and therapeutic considerations of this uncommon entity.
Al-Kahil et al. (Thu,) studied this question.