Patients undergoing revision bariatric surgery showed significantly improved metabolic parameters, including lower triglycerides and HbA1c, compared to first-time surgery patients (P < 0.003).
Does a history of previous bariatric surgery improve metabolic profiles in patients awaiting bariatric surgery compared to those awaiting first-time surgery?
Previous bariatric surgery confers lasting metabolic benefits, including improved lipid and glycaemic profiles, even in patients experiencing weight regain requiring revision surgery.
Absolute Event Rate: 0% vs 0%
Abstract Introduction Bariatric surgery is the surgical modality for treating obesity. It involves anatomical modification of the gastrointestinal tract (GIT) bypassing the upper part of the GIT which increases Glucagon-like Polypeptide 1 (GLP1), Peptide Y Y (PYY), Fibroblast growth factor, (FGF) 19,21 and other satiety hormones. This improves, glycaemic, lipid and inflammatory profiles. Objectives To assess the lasting effect of metabolic profile benefits, even in the presence of weight regain, which is a clear observation in the clinical context. Methods Retrospective data collection was conducted with age, sex and BMI matched 204 patients awaiting bariatric surgery at Rochester Regional Health. Two groups consist of first-time surgery (no history of bariatric surgery) patients, and revision surgery patients. (who has undergone bariatric surgery in the past) Demographics (age at surgery, sex, ethnicity, marital status), anthropometry (weight at surgery, height, BMI at surgery), fasting glycaemia, HbA1c, alanine transaminase (ALT), aspartate transaminase (AST), Lipid profile: total cholesterol, triglycerides, LDL, HDL, total protein, iron, ferritin, haemoglobin, and C-reactive protein, systolic and diastolic blood pressure, and other co-morbidities (diabetes, hypertension, hyperlipidaemia). The chi-square test and student t-test were applied to see the difference between the two groups. Results Patients in the revision surgery group who have once undergone bariatric surgery in the past had significantly protective investigation results in multiple metabolic parameters: lipid Profile; triglyceride, HDL, non-HDL, LDL, and Cholesterol/HDL ratio were (P = 0.003), (P = 0.003),(P = 0.006),(P = 0.021),(P = 0.001),respectively. HbA1c (P = 0.006), Fasting plasma glucose; FPG (P = 0.001) and inflammatory markers; C-reactive protein (P = 0.028). Conclusion Patients who have previously undergone bariatric surgery, despite experiencing weight regain, continue to show metabolic benefits, including improved lipid profiles, better glycaemic control, and reduced inflammatory markers, compared to those who have never undergone the procedure.
Malwatta et al. (Thu,) reported a other. Patients undergoing revision bariatric surgery showed significantly improved metabolic parameters, including lower triglycerides and HbA1c, compared to first-time surgery patients (P < 0.003).