Both HIIT and MIIT improved peak VO2 by ~2.6-2.8 ml/kg/min, reduced blood pressure, and were safe with <1% mild adverse events in high-risk CVD patients over 4 weeks.
Does high-intensity interval training improve cardiorespiratory parameters compared to moderate-intensity interval training in high risk patients with cardiovascular disease?
Both 4-week high- and moderate-intensity interval training are safe and effectively improve cardiorespiratory fitness and blood pressure in high-risk patients with cardiovascular disease.
Absolute Event Rate: 0% vs 0%
Abstract Background To investigate the efficacy and safety of high- and moderate-intensity interval training (HIIT and MIIT) in high risk patients with cardiovascular disease (CVD). Methods We recruited 161 high risk consecutive patients with CVD in a cardiac rehabilitation clinic between February 2021 and June 2023. Patients were assigned to the HIIT (n=80), and MIIT (n=81) groups, and both completed 4 weeks of exercise training. MIIT contains 4 sets×8-minutes at a rating of perceived exertion (RPE) (Borg scale of 6-20) of 12-14 along with a 2-minutes rest in between. HIIT is consists of 20 cycles×30-second at an RPE of 15-17 with a 30-second complete rest in between. Cardiorespiratory and physical health parameters were measured at baseline and follow-up, and were compared among MIIT and HIIT groups. Linear mixed-effects models for analyzing repeated measures were used to test the effects of time×group interactions. Results The median age was 54 years, and 65% were male. The changes in peak volume of oxygen uptake (peak VO2), anaerobic threshold (AT) VO2 and oxygen pulse in HIIT vs. MIIT were 2.6 vs. 2.8 ml/Kg/min; 1.7 vs. 1.8 ml/Kg/min; 1.2 vs. 0.9 ml/beat mean difference, all P=0.000). Resting systolic and diastolic blood pressure both decreased after HIIT and MIIT (all P＜0.05). Both HIIT and MIIT were safe with few mild adverse events (＜1%), and the compliance did not differ between the groups (P=0.779). Conclusions Our findings suggest that both HIIT and MIIT after 4 weeks of exercise training demonstrated larger improvements in peak VO2, AT VO2 and oxygen pulse in high risk patients with CVD. Both HIIT and MIIT resulted in greater reductions in blood pressure. Both HIIT and MIIT were safe and can be considered as efficient and safe therapeutic methods for high risk patients with CVD.Graphical abstract Flow chart
Abudoukelimu et al. (Sat,) reported a other. Both HIIT and MIIT improved peak VO2 by ~2.6-2.8 ml/kg/min, reduced blood pressure, and were safe with <1% mild adverse events in high-risk CVD patients over 4 weeks.