Comparison of dexmedetomidine and morphine versus plain ropivacaine 0.2% for myofascial infiltration in thoracolumbar spinal fusion: a double-blind randomized trial | Synapse
February 12, 2026Open Access
Comparison of dexmedetomidine and morphine versus plain ropivacaine 0.2% for myofascial infiltration in thoracolumbar spinal fusion: a double-blind randomized trial
Key Points
The study aims to compare the analgesic effects of dexmedetomidine-morphine versus ropivacaine in thoracolumbar spinal fusion surgery.
Comparison of analgesic combinations: dexmedetomidine-morphine vs. ropivacaine
Morphine-ropivacaine combination showed superior efficacy
Dexmedetomidine-ropivacaine was less effective
Ropivacaine alone resulted in the least effective pain management
Abstract
Morphine as an adjuvant to ropivacaine showed superior efficacy compared with dexmedetomidine-ropivacaine or ropivacaine alone in patients undergoing elective thoracolumbar spine fusion surgery.