Cost minimization and budget impact model for introducing the fully liquid combined acellular hexavalent vaccine into the Dominican Republic’s expanded immunization plan | Synapse
February 13, 2026
Cost minimization and budget impact model for introducing the fully liquid combined acellular hexavalent vaccine into the Dominican Republic’s expanded immunization plan
Key Points
The aim is to evaluate the economic implications of introducing a hexavalent vaccine into the Dominican Republic's immunization plan.
Cost minimization analysis performed
Budget impact model utilized
Comparison of adverse events and logistics costs
Increased spending due to vaccine introduction
Reduction in adverse events associated with vaccination
Lower logistics costs and productivity losses observed
Abstract
The incorporation of the hexavalent vaccine increases spending but reduces adverse events, logistics cost, and productivity losses, supporting modernization of the DR immunization program.