This two-sample Mendelian randomization analysis did not identify a statistically significant association between asthma and global cortical metrics. While nominal associations were observed between asthma and changes in parahippocampal and caudal anterior cingulate, these findings did not remain significant after correction for multiple comparisons and should be interpreted as exploratory. Further research is needed to elucidate potential neuroanatomical alterations associated with asthma.
Zhang et al. (Wed,) studied this question.