What question did this study set out to answer?

The aim is to explore how low-frequency rTMS affects cortical changes and motor recovery following a stroke.

February 14, 2026Open Access

Investigating repetitive transcranial magnetic stimulation–induced interhemispheric changes in stroke: a transcranial magnetic stimulation and fNIRS study

Key Points

The aim is to explore how low-frequency rTMS affects cortical changes and motor recovery following a stroke.
Applied low-frequency rTMS to stroke-affected regions.
Monitored cortical activity using transcranial magnetic stimulation (TMS) and functional near-infrared spectroscopy (fNIRS).
Analyzed changes in cortical excitability and connectivity patterns.
Demonstrated that rTMS promotes motor recovery after stroke.
Showed a rebalancing of cortical excitability post-treatment.
Reduced maladaptive connectivity patterns were observed, indicating enhanced cortical plasticity.

Abstract

We showed that low-frequency rTMS promotes motor recovery after stroke by rebalancing cortical excitability and reducing maladaptive connectivity patterns. The integration of TMS and fNIRS provides converging evidence for rTMS-induced cortical plasticity and highlights the potential of these tools for guiding personalized neuromodulation strategies in stroke rehabilitation.

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Cite This Study

Yang et al. (Tue,) studied this question.

synapsesocial.com/papers/699010382ccff479cfe56c73 https://doi.org/https://doi.org/10.1117/1.nph.13.s1.s13010

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