The effect of exogenous ketone monoester supplementation on cerebral blood flow and functional brain characteristics in adults with subjective cognitive decline: study protocol for a randomized crossover trial

Key Points

• Investigate the impact of exogenous ketone monoester supplementation on cerebral blood flow and cognitive function in adults showing early cognitive decline.
• Randomized crossover trial design
• Administration of exogenous ketone monoester supplementation
• Measurement of cerebral blood flow and functional brain characteristics
• Assessment of subjective cognitive decline in participants
• Expected improvement in cerebral blood flow after ketone supplementation
• Potential enhancement of cognitive function indicators
• Findings may reveal the role of ketones in addressing cognitive decline