Brain Network Patterns in Patients With Multiple System Atrophy | Synapse
February 14, 2026
Brain Network Patterns in Patients With Multiple System Atrophy
Key Points
The research aims to investigate the metabolic abnormalities in multiple system atrophy and their relation to brain network patterns.
Analyzed brain imaging data.
Identified large-scale brain networks involved in metabolic abnormalities.
Decomposed metabolic patterns corresponding to different disease mechanisms.
Five large-scale brain networks were identified.
The findings provide a comprehensive understanding of MSA mechanisms.
Patterns suggest variability in metabolic function across patients.
Abstract
This study demonstrated that the metabolic abnormalities in MSA can be decomposed into 5 large-scale brain networks, providing a comprehensive understanding of the disease's heterogeneous mechanisms.