What question did this study set out to answer?

To report a case of preseptal and orbital inflammation linked to bisphosphonate treatment.

February 14, 2026JAMA Ophthalmology2 citations

Bisphosphonate-Associated Orbital Inflammation

DKDanielle KundertUniversity of Basel TETim J. EnzUniversity of Basel BBBenito K. BenitezUniversity of Basel

Key Points

To report a case of preseptal and orbital inflammation linked to bisphosphonate treatment.
Case report detailing the patient's history and treatment
Administered intravenous zoledronate for osteoporosis
Monitored symptoms and inflammation post-treatment
Diagnosis of preseptal and orbital inflammation confirmed
The inflammation arose after administration of zoledronate
Symptoms occurred in a 64-year-old woman following treatment

Abstract

This case report describes a diagnosis of preseptal and orbital inflammation after intravenous infusion of the bisphosphonate zoledronate for osteoporosis in a woman aged 64 years.

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