The interpretation of pediatric thyroid lesion represents a challenging diagnostic tool for fineneedle aspiration cytology (FNAC). As for the adult lesions, it represents the first diagnostic tool for correct characterization of these nodules. Recent data from the National Cancer Institute (NCI) have proven that the incidence of thryoid malignancy has been increasing especially in adolescents. These data are mostly linked to an estimated higher prevalence of well-differentiated cancers with 90% diagnosed as papillary thyroid cancer (PTC), with some specific malignant subtypes, such as diffuse sclerosing subtype, are more frequently diagnosed in children, with, not uncommonly, a more aggressive behavior which justifies the increased number of surgical procedures. For this reason, the American thyroid association (ATA) recommended the performance of neck ultrasonography and FNAC in the evaluation of pediatric thyroid nodules. In this regard, the performance of an FNAC has high sensitivity and diagnostic accuracy in pediatric series, sharing the same problematic issues encountered in adult population, mostly in the diagnosis of the indeterminate lesions. Since 2023, the diagnosis of a pediatric lesion was based on the risk of malignancy used for the adulthood. The introduction of the third edition of The Bethesda system for reporting thyroid cytopathology (TBSRCT)introduced a specific adoption of diagnostic categories combined with their personalized ROM and management in pediatric thyroid lesions. We focused on the analysis of the ROM and data from literature hinged on the evaluation of the adoption of the TBSRTC in pediatric thyroid lesions
Taccogna et al. (Fri,) studied this question.