Characterization of tumour microenvironment in thymic epithelial tumours of different histological subtypes

Key Points

• The research aims to analyze the tumor microenvironment and identify biomarkers in thymic epithelial tumors.
• Conducting an integrative analysis of different thymic epithelial tumor subtypes.
• Characterizing the tumor microenvironment (TME) for each histological subtype.
• Identifying immunometabolic biomarkers associated with aggressive tumors.
• Demonstrated evolutionary divergence among thymic epithelial tumor subtypes.
• Identified heterogeneity in the tumor microenvironment across different TETs.
• Relevant immunometabolic biomarkers may aid in prognosis and treatment strategies.